side effect of justicia carnea

Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. 2007;112(1):13844. 2007;39(1):4484. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). MacRae, W. D. and Towers, G. H. Justicia pectoralis: a study of the basis for its use as a hallucinogenic snuff ingredient. et al. J Afr Ass Physiol Sci. J Ethnopharmacol 2000;70(2):151-159. Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. 1983;53:27589. Create a beautiful garden with this colorful and Use our interactive toolsto design your dream garden. However, coadministration of both extracts exerts a synergistic effecton the . It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. View abstract. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Justicia carnea belongs to the family- Acanthaceae. J Ethnopharmacol. The spread is equally glorious and can take up 12 15 inches of space. https://doi.org/10.1016/j.jada.2008.06.430. The perennial plant puts on a never-ending show of radiant flowers from early spring to fall. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. Inter J Pharm Sci Res. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. Fitoterapia. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. If you provide us with your name, email address and the payment of a modest $25 annual membership fee, you will become a full member, enabling you to design and save up to 25 of your garden design ideas. Inflammation is a complex biological response of body's tissue to harmful stimuli like infections, toxins and itself. Sci. Prevent this by spraying the leaves with water. J Ethnopharmacol. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. PubMed Author ESA managed the literature searches and wrote the first draft of the manuscript with the assistant of FOA. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Onoagbe IO, Attah V, Luther MM, Esekheigbe A. Hypoglycemic and anti-diabetic effects of Morinda lucida and Tetracera alnifora in normal and streptozotocin-induced diabetic rats. Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. W Afr J Biol Sci. Mukinda JT, Syce JA. One of the oldest known plant is the fig tree. Rats that received 50 and 100mg/kg body weight JCEE showed significant (p<0.05) increase in liver weight while other doses showed no significant difference compared to the control. Pinch Justicia carnea plants back after theyve flowered. Chanda S, Parekh J, Vaghasiya Y, Dave R, Baravalia Y, Nair R. Medicinal plants - from traditional use to toxicity assessment: a review. 2. However, the mechanism by which phytochemicals act as prooxidants in-vivo is still under investigation [25]. Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. The effect of the ethanol extract of Justicea. This encourages better flowering and bushier and denser new growth. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. Clin Phytosci 7, 2 (2021). Not sure which Justicia to pick?Compare All Justicia. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. They also maintain our skin tone and texture, and help in reproductive functions. 1978;52:30210. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. In which ever condition, the blood glucose level increases abnormally. In phase two, three rats were separated into 3 groups of one rat per group. Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. J Ethnopharmacol 1984;12(1):93-111. Information from this source is evidence-based and objective, and without commercial influence. A cup of ewe eje extract in the morning will provide you with energy needed to pull through the days activities. Vitamin C and E are antioxidants. Washington, DC: The National Academies Press; 1997. https://doi.org/10.17226/4988. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. CAS All authors read and approved the final draft of the manuscript. J Ethnopharmacol. Macrocytic and hypochromic anemia usually results due to increased mean corpuscular volume (MCV) and decrease in mean corpuscular hemoglobin concentration [30]. Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. In subacute study, rats were randomized into six groups of five rats per group: Group 1 (control) received distilled water, group 2, 3, 4, 5, 6 received 50, 100, 500, 800 and 1200mg/kg body weight of J. carnea ethanol extract once daily using oral gavage. Hence, Justicia carnea can be used to strengthen the immune system. statement and In these groups, from mild to severe order; the renal cortex appears distorted, Renal glomeruli and dillated capsular spaces appeared collapsed with characteristic pyknosis of the mesangial cells, The renal tubules, interstitial spaces, appears distorted with presence of red inflammatory cells, hemorrhagic cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane (red arrows). degree in Biochemistry from Olabisi Onabanjo University, Ago-iwoye, and University of Ibadan, Ibadan, Nigeria respectively. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. 2015;15:236. https://doi.org/10.1186/s12906-015-0760-y. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. 2015;6(7):265270. However, scientifically it is called Justicia carnea. They should be watered regularly (once per week), but not overwatered. long (20 cm), densely packed with pink to crimson tubular flowers. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Article Omogunwa is a graduate of Biochemistry from the Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Braz. 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. It is an awesome plant and worth your time and attention. Studies have shown that ewe eje isnt capable of causing damage to the liver. 16. A cup of water 2011;5(9):48992 https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867. long (20 cm), densely packed with pink to crimson tubular flowers. Filed in Biochemistry Project Topics, Current Projects by TMLT Editorials on September 22, 2020. Keep in mind that natural products are not always necessarily safe and dosages can be important. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. After 72h of soaking, the wine (dark purplish red) colored filtrate was filtered using a double cheese cloth, concentrated under reduced pressure using rotary evaporator and subsequently water bath at 40C to obtain a slurry (dark purple) extract termed Justicia carnea ethanol extract (JCEE). The species Justicia secunda Vahl belongs to the family - Acanthaceae - together with up to 600 other shrubs and herbs species. The description of these plants has been written based on numerous outside resources. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. Aim. 1978;90:819. 2). Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). The indistinguishable differences of total protein in the liver and kidney of rats treated with ethanol extract of J. carnea could indicate that the plant extract did not alter protein synthetic function of the organs. Water your plants deeply during growth periods, allowing the soil to dry . Evid Based Complement Alternat Med. Sedlak J, Lindsay RH. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. Further, 0.5ml of supernatant was treated with 0.5ml of Ellmans reagent (containing 19.8mg of 5,5 dithiobis - (2-nitrobenzoic acid) (DTNB) in 100ml of 0.1% sodium nitrate) and 3.0ml of phosphate buffer (0.2M, pH8.0). Canadian J Appl Sci. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. The fresh leaves were thoroughly washed under running tap, air dried under shade, pulverized and extracted with ethanol. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). Faiza R, Waqas KK, Adeel M, Muhammad G. Detection of bioactive fractions of Justicia adhatoda leaves. Lorke D. A new approach to practical acute toxicity testing. van Andel T., Carvalheiro LG. (2017). Dyslipidemia is one of the risk factors of cardiovascular diseases. Powdered sample was extracted using absolute ethanol and concentrated to obtain a slurry paste of J. carnea ethanol extracts. J Ethnopharmacol 1999;64(3):265-270. Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. Why urban citizens in developing countries use traditional medicines: the case of suriname. These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. Leal, L. K., Ferreira, A. Too much sun can scorch the leaves, and too little will result in fewer flowers. J Ethnopharmacol. CAS When you boil the plant, it turns the water red. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. https://doi.org/10.1016/j.biocel.2006.07.001. The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. The LD50 of extract was greater than 5000mg/kg body weight. The effects of ethanol extract of J. carnea leaf on total protein concentration and antioxidant system in liver and kidney of normal wistar rat is presented in Table 4. Antioxidants & redox signaling Forum Review. Ewe eje as a Natural Blood booster/tonic: Due to the high concentration of iron in this leaf, it can help boost blood production by increasing the red blood cells, haemoglobin, and the blood platelets. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Beijing: Chemical Press; 2011. Different drugs are used but many depend mainly on plants and herbal products for its treatment. 4. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. This later condition is termed insulin resistance. The efficiency of some preexisting anti-obesity drugs was limited by several adverse effects associated with them including gastrointestinal disorder, high risk of cancer, and long-term use detrimental effects on some organs such as liver, kidney and pancreas [ 4, 8 ]. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. While vitamin A maintains good vision, vitamin B are good for cellular functions such as metabolisms and energy production, and improve brain functioning. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. https://doi.org/10.1016/j.jep.2007.02.011. In this study, nutritive potentials and effects of aqueous extract of Justicia carnea leaves on biochemical indices of anaemic male Wistar albino rats were investigated. Nutritional Composition of Ewe eje (Justicia carnea leaf). Anthonia OC, Ikechukwu UR, Uzoma NO, Sunday ELU. Kidney weight of rats treated with JCEE showed no significant difference with exception in 800mg/kg JCEE that demonstrated significant reduction. Make sure to follow the package instructions carefully. Other English names for this plant include: flamingo flower, Jacobinia, Brazilian plume flower and Brazilian plume. Justicia carnea is amedicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. This post was last modified on January 2, 2023 5:23 pm. 2013;1:38898. This is in agreement with study of Anthonia et al., [21] who obtained LD50 above 5000mg/kg for aqueous extracts of J. carnea leaf. The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. 2008;108(9):14807. Over time, they cause atherosclerosis and myocardia infarction. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. The major use of Justicia carnea leaves is to improve blood production. The lush foliage and distinctive flowers make Brazilian Plume a natural for a . Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. Aim. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. View abstract. Onyeabo, Chimaraoke & Achi, Ngozi & Chima, Ekeleme-Egedigwe & Ebere, Chidinma & Okoro, Chidinma. 2004;19(12):16. Haematological and biochemical studies on Justicia carnea leave extract in phenylhydrazine induced-anemia in albino rats. Yes my readers. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. Elevated activity of catalase in liver and kidney across tested doses of J. carnea ethanol extract showed no significant effect compared to the control. However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. 2005 - 2023 WebMD LLC, an Internet Brands company. Haematoxic effects following ingestion of Nigerian crude oil and crude oil polluted shellfish by rats. Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. The levels of white blood cell count, lymphocyte, granulocyte and MID could indicate that ethanol extract of J. carnea leaf pose no toxicity or sub acute inflammation to the overall defense mechanism and immunity of the experimental rats. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in Bottom Line. Toxicity studies of medicinal plants used in sub-Saharan Africa. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. Anal Biochem. In this report, MCV, MCH and MCHC in treated group were not altered compared to the control. Different drugs are used but many depend mainly on plants and herbal products for its treatment. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. J Am Diet Assoc. Pinch out tips to promote compact plants. https://doi.org/10.4314/njps.v19i1.32627. In-vivo studies have revealed that radicals produced from these dietary antioxidants are constantly regenerated back to their active form by GSH in the ascorbate glutathione cycle. Research reports it isn't capable of . J Nat Prod 1988;51(3):599-600. One of the symptoms of diabetes is elevated blood glucose level. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Side effects of Ewe eje (Justicia carnea leaf Side Effects). 1. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. 2003;84:99104. Google Scholar. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). Despite living in close proximity to this plant, many individuals may be unaware of its benefits. The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. Deleting this collection CANNOT be undone. This leaf replenishes your blood supply immediately. J. Pharmacogn. The hematopoietic systems represent a sensitive target of toxic compounds and an essential index of physiological and pathological status in experimental animals [24]. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Parameter that were determined include total haemoglobin concentration (HGB), packed cell volume (PCV), red blood cell count (RBC), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV), white blood cell count (WBC), Lymphocyte count (LYM), MID sized cell (MID), Granulocyte Count (GRM) and platelet count (PLT). These tropical plants are not very fussy about soil. The resultant liquid would turn crimson red. The aim of this study is to evaluate the effects of J. carnea leaf extract on hematology indices and organ antioxidant system in healthy wistar rats. Fresh leaves of Justicia carnea were collected from Okitipupa area Ondo State. Rich on haematological and biochemical parameters in healthy Wistar rats. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Justicia Carnea is a flowering plant that may be found in our neighborhood. They are also needed in strong bone formation, and in cellular and neuronal functions. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. From this study, the significant increase in platelet counts suggested that the extract could be useful in preventing excessive blood loss (through blood clotting) and resistance of capillary membranes to leakage of red cells when blood vessels are damaged. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. It also grows in some Caribbean islands, including Trinidad and Tobago. Add organic matter or compost in the soil and place the plant. The roots and the leaves possess medicinal values and have been used in treating several diseases. This is . Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. Ogwu obara is commonly used in making porridge yam, and soups. In a pot, pour in a cup of water and bring to a boil. 2019;30(4):64554. View abstract. In an acute exposure of experimental rats to single oral doses of extract, no mortality and signs of adverse effects were observed. Walters DM., Cho Hye-Youn, Kleeberger SR. Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2. Control treatment showed normal central venules without congestion, the morphology of the hepatocytes appear normal, the sinusoids appear normal with no observable form of infiltration and no observable pathological lesion seen. Ren Fail. Article Acute and chronic toxicity of the aqueous extract of Artemisia afra in rodents. Accept Justicia carnea needs bright, indirect light to thrive. The concentration of reduced glutathione content of the tissues was estimated according to Sedlak and Lindsay [19] method. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. I am a practicing medical doctor, a philosopher, critical thinker, a globalist, a patriot, SEO expert and a patient blogger. In sub-acute toxicity study, total of thirty (30) rats were randomized into six groups of five rats per group: Group 1 served as control and was administered with 1ml of distilled water (dH2O). In this study, the aqueous leaf extract of Justicia carnea was used. The ameliorative effect of Justicia carnea on blood glucose level and lipid profile in alloxan-induced diabetic albino rats was evaluated in a study titled, "Effects of methanol leaves extract . Rats were further observed for extended hours of 48h to see if mortality would occur. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. Justicia carnea has been used in traditional medicine to treat diabetes. Prof. F.O. Also present in the leaf extract are minerals (such as magnesium, copper, iron, zinc, calcium); and vitamins (such as vitamins A, C, E and B-vitamins). Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. You can add the leaves and water altogether in a pot and allow to boil till the water turns red. Diallo A, Gbeassor M, Vovor A, Eklu-Gadegbeku K, Aklikokou K, Agbonon A. Having discussed the nutritional benefits of ewe eje, i shall now take you through the various health benefits of justicia carnea leaves, and roots. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. CAS Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). The absorbance was read at 412nm against the reagent blank. Proximate analysis of the aqueous extract of J. carnea leaves showed that it contains appreciable amounts of 53.07 0.07% carbohydrate, 9.26 0.02% ash, and 26.71 0.02% . This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. The in-vitro . In this study, the aqueous leaf extract of Justicia carnea was used. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. Meth Enzymol. https://doi.org/10.35841/biomedicalresearch.30-18-666. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. Note this is the default cart. Google Scholar. It also grows in some Caribbean islands, including Trinidad and Tobago . Molecules (Basel, Switzerland), 19(12), 2144221461. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. Paes-Leme AA, Motta ES, De Mattos JCP. Terms and Conditions, Google Scholar. Uses, Benefits, Cures, Side Effects, Nutrients in Justicia Betonica. This information may not fit your specific health circumstances. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. The compound responsible for this activity is lignan. 2017;16(2):21730 https://doi.org/10.17306/J.AFS.2017.0492. Ewe eje is a rich source of phytochemicals, minerals and vitamins. Summer temperatures above 77 degrees Fahrenheit (25 C) are perfect. As a consequence, depletion of reduced glutathione (GSH) either by removal from the cell or oxidation to GSSG could eventually lead to mild oxidative stress in cells and tissues [33, 34]. This is in agreement with previous work on the reversed effect of J. carnea leaf extract on anaemia induced experimental rat [9, 21]. 50mg/kg-1200mg/kg treatments relative to control showed varied degree of hepatic injury that is dose dependent. The leaves of Justicia carnea contains powerful antioxidant activities and phytochemical components that help reduce oxidative stress, and reduce the risk of development of cancer.

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side effect of justicia carnea