(Pat Greenhouse/Globe Staff), David Sabatini sat on the doorsteps at his home in Cambridge last September. Sabatini told the Globe he learned from his lawyer he was going to be fired at the 1 p.m. meeting. Knouses allegation, though initially vague, landed like a ticking time bomb in Lehmanns lap. He was 50. Earlier this week, he says, I called him and said, We think its important that you get back to work., Looking for a partner to split the costs of relaunching the Sabatini lab, Ackman says he next called two potential donors. Come join our interdisciplinary team as we unite technology development and biological discovery to understand and modulate organ regeneration! My father will die before this is cleared up. . This case is about David Sabatini, M.D., Ph.D. ("Sabatini" or "Counter-Claim . He jumps at the chance to talk science when his former lab members reach out. The report details the starkly diverging narratives from Knouse and Sabatini about what led them to have sex for the first time April 18, 2018, in Sabatinis hotel room at Marylands Rockville Hotel after a night of drinking and dinner at a restaurant in Washington D.C. He had split with his wife, and was in. Lehmann acknowledged that some lab members raised concerns about the Hinckley investigation, and she was later assured, after speaking to the investigators, that they were making every effort to minimize stress in the lab. Sabatinis paychecks stopped. But a summer high school science enrichment program lit the spark, and her undergraduate studies at Duke and graduate work at the Harvard/MIT MD-PhD program only confirmed her love of biological research and her uncommon gift for the work. Such a relationship was strictly barred under Whitehead policies, and of course he knew that, too. In conclusion, the investigators placed Sabatini at the center of the blame, writing: These findings, in the aggregate, portray a high-achieving but troubled laboratory led by a brilliant but personally flawed and immature scientist whose management of a diverse, talented and vulnerable workforce is inconsistent, arbitrary and, at times, lacking in professionalism and social awareness.. Note: Text exchanges between individuals in this story are animated. And then, in an arrangement that she later told confidantes caused her increasing unease, they had casual and clandestine sex. On her first day as Whitehead director that July, she had promised to foster a culture of excellence and about a week later, commissioned a firm to conduct a diversity, equity, and inclusion survey of all staff. Kristin Knouse seeks to understand and modulate organ injury and repair by innovating tools for experimentation directly within living organisms. Deeply damaging to Sabatini was the revelation he had had a past sexual relationship with a brilliant young Whitehead scientist with a similar title but much less research experience and stature, Kristin Knouse, in her early 30s. Office. She told human resource officials that Sabatini showed more personal attention to attractive lab members and that female trainees deliberately flirt a little with Sabatini because they believe it will boost their careers. Many powerful figures in Sabatinis situation might have responded to such a potentially career-destroying crisis with contrition and humility. Sabatinis hopes for a second chance evaporated. It was a head-snapping turn of events: Top scientists at another leading research institution had reviewed the case and reached a much more forgiving conclusion, one that gave Sabatini a chance to salvage his career. Meanwhile, Lehmann, early in her tenure at Whitehead, was facing a nightmarish personnel crisis around one of the institutes most prominent scientists who brought in massive research dollars. It was abundantly clear to me that Angelika thought that this was inappropriate, Weis said, and it was Davids job not to let it happen.. She said she felt she could not say no to him because of his stature in the field, and potential influence on her career, and eventually yielded to having sex. In November, she published a paper in Cell Genomics about her labs development of a novel technology that will allow researchers to investigate the function of every gene in a living mammal. I hope that we can undertake honest, productive, and difficult conversations together, said Lehmann, then 65, in an email to all employees on her first day as the head of Whitehead. Kristin Knouse @kristinknouse. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. A probe there found that he had violated its policies on consensual sexual relationships by entering an undisclosed sexual relationship with Knouse when she was in the final months of an M.D.-Ph.D. program and he was in a position to influence her career. KRISTIN KNOUSE, M.D., PH.D.'S COMPLAINT IN COUNTERCLAIM1. Soon after, a potential job offer for Sabatini at New York University fell apart after student and faculty protests. And she dismissed a move by Knouses lawyers to have Sabatinis lawsuit against her thrown out under a Massachusetts law aimed at preventing people from using lawsuits to intimidate others from expressing themselves in legislative, executive, and government proceedings. High up in the report, they accused him of obstruction, for engaging with lab members in violation of Lehmanns directive, and there was also the critical question of Sabatinis credibility. in the jurisdiction of Suffolk County, MA. And, in what would prove to be a test of whether she could trust him, she explicitly ordered him not to try to interfere with the investigation in any way. Knouse had also told them of seemingly contradictory emotions about Sabatini, sometimes apparently wanting more from him, other times complaining about being exploited. He felt his only recourse for a fair hearing was in the courts. Sabatini and Knouse had met in 2012, when she was a star student in a graduate course Sabatini co-taught at the . Assistant. It would be the beginning of Sabatinis undoing. Her emotions evolved to something else. Assistant Prof @MITBiology @kochinstitute. They often do, but not enough to fill all his time. On Dec. 29, she and Sabatini appeared in the Cambridge city clerks office and married. [And] Mr. Ackman would like to set us back by decades. The ruling is the latest twist in a saga that began when Sabatini, who made his name with groundbreaking discoveries on mammalian cell signaling, was fired by the Howard Hughes Medical Institute and forced out of the Whitehead Institute in August 2021. Their relationship began before Knouse arrived at Whitehead, when she was an MIT graduate student. Failure to abide by these strong recommendations will be considered a serious breach of trust.. It scheduled a Zoom presentation for principal investigators and fellows to explain the results on March 25, 2021. The judge opined that that claim appears to be weak but Sabatinis arguments minimally state a claim she would allow to proceed. Soon, more of Knouses account, full of nuance and complications and assertions that Sabatini furiously disputes, would emerge. She said she came to think that the depiction of Sabatinis lab as having a toxic atmosphere was wrong. He doesnt care because he doesnt have to worry about the graduate students whose career may be ended by a powerful person.. Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Sign up to receive Spotlight reports and special projects in your inbox. My life was 100 percent destroyed, he told the Globe. But, Ackman says, the second potential donor told him, This is the best idea I have heard in a long time., Ackman declined to name the individual, but said the name will eventually become public. 2023 American Association for the Advancement of Science. Gretchen Ertl/Whitehead Institut. | In a counterclaim filing against MIT professor David Sabatini, his former mentee and Whitehead Institute colleague alleges he "coerced" her into sex and led a "highly sexualized" lab. How much U.S. forest is old growth? Hours after receiving the report, Sabatini got an e-mail from Erin OShea, president of the Howard Hughes Medical Institute, asking him to be part of a meeting the next day, on Aug. 20, at 1 p.m. Lehmann was also scheduled to be part of the same scheduled meeting. He said nothing, just watched the bird hop away, free. Knouse was an incoming cancer researcher at the Whitehead, where she would also head her own lab; hers focused on liver regeneration. How much U.S. forest is old growth? She has crafted Whiteheads values statement and said Whitehead also adopted Jones Diversitys recommendations, including for DEI training. We werent ready to make a deal with him, but we felt he was an outstanding talent and hadnt done anything that would prohibit our interest in him.. This followed a probe by an outside law firm that concluded he broke the institutes sexual harassment policy by cultivating a hidden sexual relationship with Knouse, a mentee who was then launching her own lab at the Whitehead Institute. NYU was considering offering him a non-tenured position for a trial period, with an out-clause so the school could freely dismiss Sabatini if more derogatory information surfaced. All of Whitehead's principal investigators have faculty positions at MIT. Its not bro culture backing up the guys. Beyond the fact of their sexual entanglement, he had been at times a special mentor to her, and having an influential patron is critical to success in the rarefied upper echelons of science. She said that she continued to acquiesce and have sex with him on other occasions, but that her mind was full of mixed feelings. Assistant Phone. On March 1, 2022, Sabatini took a train to Manhattan. She also wanted to expose the powerful scientist she believed might hurt other vulnerable women. Percentage of people of color who felt they need to hide a part of their identity to assimilate at Whitehead, about twice that of white respondents. Sabatini was asked to attend another Zoom meeting the next morning, with Whitehead board members Susan Hockfield, a former MIT president, and Phillip Sharp, an MIT biology professor and a 1993 Nobel Prize winner. The subcommittee included not just Lehmann, Hockfield, and Sharp, but three prominent members of the business community and MIT economic professor Paul Joskow. He could say that he ASSURED me that i could push of his advances and that he wasnt my direct supervisor etc etc, and then he just gets a small slap on the wrist. At the time Sabatini was about 50 years old . After decades immersed in laboratory life, she knew that sexual harassment against women in science was all too common and that any probe would inevitably convulse the workplace, unleashing forces that could blow up into lawsuits, disruption, and truth-twisting social media storms. (Knouse is now a tenure-track scientist at MIT.) But Lehmann insisted significant change is well underway. If women who are sexually harassed are sued for daring to report it, the result is clear: there will be no reporting.. 520-784-1810. His mail slot was stuffed daily with notices from organizations cutting ties with him. As far as the outside world could see, she and Sabatini were colleagues and friends, but the truth was that, off and on for more than a year, they had had about a dozen secret sexual liaisons secret because, beyond wanting to avoid eyebrow-raising gossip, they knew that such relationships between scientists in their positions were strictly forbidden at the Whitehead. He said he asked to speak to Lehmann as the investigation began, but Lehmann declined, saying she wanted to let the investigation play out. But Judge Hlne Kazanjian in a 30 March ruling declined to dismiss what Sabatini called the most important one, alleging workplace discrimination. At this time, Dr. Sabatini was a world renowned . After hearing Sabatini out, Bar-Sagi thought the public version of the Sabatini story was, at the very least, incomplete. It was clear that in the credibility contest between Sabatini and Knouse, the investigators overall believed Knouse. Percentage of administrative and support staff who said they felt comfortable reporting offensive comments to leadership, but only 11 percent of scientific researchers felt the same, suggesting a more tenuous connection to the institution. Ive been here forever. According to Knouse, she was coaxed that night to lie on the bed next to him, even as she told him that this was a bad idea. (Knouse) told investigators that part of her wanted to be in a real, not simply sexual relationship with Sabatini, but that she knew that the ongoing sexual relationship with Sabatini had been the source of her deep mental health struggles, lack of productivity, and unhappiness.. They separated in mid-2021, before the investigative report came out, and then divorced. Its unequivocally not true, said one woman from the lab. And some institutions, faced with accusations about an accomplished longtime employee, might have sought or negotiated a compromise disciplinary path. A sexual harassment case that has roiled multiple research institutions took another turn last week when a Massachusetts superior court judge threw out most claims made by biologist David Sabatini against the Whitehead Institute and its president and director Ruth Lehmann in a 2021 defamation lawsuit. (Erin Clark/Globe Staff), The Sjberg Prize 2020 went to David Sabatini (right) as well as Michael N. Hall from the Biozentrum in Basel, Switzerland. Knouse later filed a countersuit, alleging sexual harassment and retaliation. Sabatini resigned from the Whitehead Institute in August after an outside law firm hired by the institute to investigate found "that Dr. Sabatini violated the Institute's policies on sexual harassment among other policies unrelated to research misconduct," according to an email Lehmann sent staff there at the time. She offered guidance. (Provided by David Sabatini). She also declined to dismiss several of Sabatini's claims against Kristin Knouse, a biologist at the Massachusetts Institute of Technology (MIT), who accused Sabatini of sexual harassment and whom he also sued in October 2021; his defamation claim against her was preserved in the ruling. It was quickly obvious to NYU officials that hiring Sabatini was impossible in the face of such controversy and division. Sabatini turned over all of his after the end of 2019, that is, after the sexual liaisons were over. Their presence at Whitehead highlighted some recent successes in diversity and inclusion efforts at the institute. The complaints of Knouse and others had been heard. Sabatinis personal life was also taking off as well and he married for the second time. Cell biology: the micronucleus gets its big break. The National Institutes of Health, a major government source of grants for Whitehead, had threatened fiscal penalties for institutions that didnt transparently, and vigorously, address issues of sexual harassment and misconduct. This hurts so much, she said in an interview during which she wept periodically. Kristin Knouse received a BS in biology from Duke University in 2010 and then enrolled in the Harvard and Massachusetts Institute of Technology MD-PhD program, where she earned a PhD through the MIT Department of Biology in 2016 and an MD through the Harvard-MIT Division of Health Sciences and Technology in 2018. Detection of Copy Number Alterations Using Single Cell Sequencing. Cambridge, MA knouselab.org . Some of the top responses to Google searches about her are about this scandal, not her science. Ackmans move sends the message that some high-profile and ethical people are willing to support David Sabatini re-engaging his brilliant career as a scientist and mentor of other scientists, despite the risk that by doing so they themselves will be falsely attacked, says Jeffrey Flier, an endocrinologist at Harvard Medical School and former dean there. Sabatini declined an opportunity to plead his case for keeping his tenured professorship before faculty colleagues and resigned from MIT as well. But if there was any doubt in his mind, it likely evaporated shortly after the probe began. 77 Massachusetts Ave, 68-132 | Cambridge, MA 02139 | 6172534701, 2019 MIT Department of Biology | Credits. Knouses texts that were shared with friends and investigators and reviewed by the Globe appear to document a gradual and wrenching evolution of her emotional state. May 21, 2022 5:35pm. It felt like the lawyers came with a thesis already made, said one former lab member. It offered a confidential way for Knouse and others to voice their concerns. This place where lab experiments once hummed, where scientists hoped to break new ground and find cures for cancer, diabetes, and Parkinsons, went quiet. Beginning in April 2018, Dr. Sabatini had a consensual sexual relationship with a friend, colleague and peer, Defendant Dr. Kristin A. Knouse. All rights reserved. Sabatini did not appear in court that day and the judge has issued no decision yet. Lehmann e-mailed back and accepted his resignation. Knouse is a young woman Sabatini had groomed while she was a graduate student under his mentorship, inviting her to social events at Education. Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues. Lehmann had only met Knouse once before, briefly, at a work retreat. Kristin Knouse seeks to understand and modulate organ injury and repair by innovating tools for experimentation directly within living organisms. He said he believed that Knouse, a woman in her early 30s who now ran her own lab, would have been comfortable saying no if she didnt want to have sex with him and that he would have respected that. We strongly disagree,Gertner and Zucker wrote. Always a good time running with both Sabatini labs (and other science/running friends)! So how am I supposed to get my life back other than to get the truth out there?. For this reason, she sought to leave Whitehead. It also found that he and Knouse carried on a sexual relationship against Whitehead rules. He said he had a strong record of supporting women. Sabatini replied that he always offered help to people who felt aggrieved and denied ever threatening to retaliate against them, according to Whitehead notes from the meeting. They brought their initial findings to Ken Langone, chair of NYU Langone Health. Last weeks decision confirmed that, despite the efforts of the defendants to delay and dismiss my case, my claims against Dr. Knouse can proceed, and the critical employment-based discrimination claims against the Whitehead Institute can also proceed. ", Nancy Gertner and Ellen Zucker, lawyers for Knouse, said in a statement: We are heartened by the Courts dismissal of certain claims brought against Kristin Knouse and by the Courts wholesale denial of Sabatinis efforts to scuttle Knouses claims against him for workplace harassment and retaliation.. In 2018, he had an open sexual relationship with a female colleague named Kristin Knouse. Two of the top litigators in the city, Gertner, the former federal judge, and Ellen Zucker, a high-powered lawyer who handles many employment cases, notified Sabatini that they had been retained by Knouse and may be filing a potential harassment and retaliation case after the Whitehead investigation was over. Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System. More than 30 percent said they heard offensive language, about topics such as race, LGBTQ status, and gender, among others. (Knouse declined several previous requests for interviews, but ultimately consented on the condition that her lawyers be present and that she would not publicly discuss her relationship with Sabatini due to his pending defamation case against her.). She was 29. But life over the past year has been far from easy. She has been the target of relentless attacks on Twitter as the woman who took down Sabatini. They published scientific papers at a prolific pace, more than 200 since he launched his lab in 1997. There was a great esprit de corps in the lab, said one member who was there in the years leading up to Sabatinis fall.
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